Effects on biota

Plants
Nitrogen fixation, which is required for the growth of higher plants, is hindered by pesticides in soil.The insecticides DDT, methyl parathion, and especially pentachlorophenol have been shown to interfere with legume-rhizobium chemical signaling.Reduction of this symbiotic chemical signaling results in reduced nitrogen fixation and thus reduced crop yields.Root nodule formation in these plants saves the world economy $10 billion in synthetic nitrogen fertilizer every year.
Pesticides can kill bees and are strongly implicated in pollinator decline, the loss of species that pollinate plants, including through the mechanism of Colony Collapse Disorder,in which worker bees from a beehive or Western honey bee colony abruptly disappear. Application of pesticides to crops that are in bloom can kill honeybees,which act as pollinators. The USDA and USFWS estimate that US farmers lose at least $200 million a year from reduced crop pollination because pesticides applied to fields eliminate about a fifth of honeybee colonies in the US and harm an additional 15%.

Classification of pesticides

Pesticides can be classified by target organism, chemical structure, and physical state.Pesticides can also be classed as inorganic, synthetic, or biologicals (biopesticides),although the distinction can sometimes blur. Biopesticides include microbial pesticides and biochemical pesticides.Plant-derived pesticides, or "botanicals", have been developing quickly. These include the rotenoids, nicotinoids, and a fourth group that includes strychnine and scilliroside.
Many pesticides can be grouped into chemical families. Prominent insecticide families include organochlorines, organophosphates, and carbamates. Organochlorine hydrocarbons (e.g. DDT) could be separated into dichlorodiphenylethanes, cyclodiene compounds, and other related compounds. They operate by disrupting the sodium/potassium balance of the nerve fiber, forcing the nerve to transmit continuously. Their toxicities vary greatly, but they have been phased out because of their persistence and potential to bioaccumulate.Organophosphate and carbamates largely replaced organochlorines. Both operate through inhibiting the enzyme acetylcholinesterase, allowing acetylcholine to transfer nerve impulses indefinitely and causing a variety of symptoms such as weakness or paralysis. Organophosphates are quite toxic to vertebrates, and have in some cases been replaced by less toxic carbamates. Thiocarbamate and dithiocarbamates are subclasses of carbamates. Prominent families of herbicides include pheoxy and benzoic acid herbicides (e.g. 2,4-D), triazines (e.g. atrazine), ureas (e.g. diuron), and Chloroacetanilides (e.g. alachlor). Phenoxy compounds tend to selectively kill broadleaved weeds rather than grasses. The acetylcholine and benzoic acid herbicides function similar to plant growth hormones, and grow cells without normal cell division, crushing the plants nutrient transport system.[11]:300 Triazines interfere with photsynthesis.[11]:335 Many commonly used pesticides are not included in these families, including glyphosate.

• Algicides or algaecides for the control of algae
• Avicides for the control of birds
• Bactericides for the control of bacteria
• Fungicides for the control of fungi and oomycetes
• Herbicides (e.g. glyphosate) for the control of weeds
• Insecticides (e.g. organochlorines, organophosphates, carbamates, and pyrethroids) for the control of insects - these can be ovicides (substances that kill eggs), larvicides (substances that kill larvae) or adulticides (substances that kill adults)
• Miticides or acaricides for the control of mites
• Molluscicides for the control of slugs and snails
• Nematicides for the control of nematodes
• Rodenticides for the control of rodents
• Virucides for the control of viruses

Pesticides can be classified based upon their biological mechanism function or application method. Most pesticides work by poisoning pests.A systemic pesticide moves inside a plant following absorption by the plant. With insecticides and most fungicides, this movement is usually upward (through the xylem) and outward. Increased efficiency may be a result. Systemic insecticides, which poison pollen and nectar in the flowers, may kill bees and other needed pollinators.
In 2009, the development of a new class of fungicides called paldoxins was announced. These work by taking advantage of natural defense chemicals released by plants called phytoalexins, which fungi then detoxify using enzymes. The paldoxins inhibit the fungi's detoxification enzymes. They are believed to be safer and greener.

History of pesticides

Since before 2000 BC, humans have utilized pesticides to protect their crops. The first known pesticide was elemental sulfur dusting used in ancient Sumer about 4,500 years ago in ancient Mesopotamia. By the 15th century, toxic chemicals such as arsenic, mercury and lead were being applied to crops to kill pests. In the 17th century, nicotine sulfate was extracted from tobacco leaves for use as an insecticide. The 19th century saw the introduction of two more natural pesticides, pyrethrum, which is derived from chrysanthemums, and rotenone, which is derived from the roots of tropical vegetables.Until the 1950s, arsenic-based pesticides were dominant.Paul Müller discovered that DDT was a very effective insecticide. Organochlorines such as DDT were dominant, but they were replaced in the U.S. by organophosphates and carbamates by 1975. Since then, pyrethrin compounds have become the dominant insecticide.Herbicides became common in the 1960s, lead by "triazine and other nitrogen-based compounds, carboxylic acids such as 2,4-dichlorophenoxyacetic acid, and glyphosate". In the 1940s manufacturers began to produce large amounts of synthetic pesticides and their use became widespread.Some sources consider the 1940s and 1950s to have been the start of the "pesticide era."Pesticide use has increased 50-fold since 1950 and 2.3 million tonnes (2.5 million short tons) of industrial pesticides are now used each year.Seventy-five percent of all pesticides in the world are used in developed countries, but use in developing countries is increasing.In 2001 the EPA stopped reporting pesticide use statistics; the only comprehensive study of pesticide use trends was published in 2003 by the National Science Foundation's Center for Integrated Pest Management. In the 1960s, it was discovered that DDT was preventing many fish-eating birds from reproducing, which was a serious threat to biodiversity. Rachel Carson wrote the best-selling book Silent Spring about biological magnification. The agricultural use of DDT is now banned under the Stockholm Convention on Persistent Organic Pollutants, but it is still used in some developing nations to prevent malaria and other tropical diseases by spraying on interior walls to kill or repel mosquitoes.